2018-05-03
Author: Dominic W. S. Wong
Publisher:
ISBN: 9783319777627
Category :
Languages : en
Pages : 250
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Book Description
Clear and concise, this easy-to-use text offers an introductory course on the language of gene cloning, covering microbial, plant, and animal systems. The essential concepts in biology relevant to the understanding of gene cloning are presented in a well-organized and accessible manner. This updated version of the first edition is an invaluable book for nonscientists as well as scientists with little background knowledge in gene cloning, providing a wealth of information for anyone wishing to gain proficiency in reading and speaking the language of gene cloning.
Author: Dominic W. S. Wong
Publisher:
ISBN: 9783319777627
Category :
Languages : en
Pages : 250
View
Book Description
Clear and concise, this easy-to-use text offers an introductory course on the language of gene cloning, covering microbial, plant, and animal systems. The essential concepts in biology relevant to the understanding of gene cloning are presented in a well-organized and accessible manner. This updated version of the first edition is an invaluable book for nonscientists as well as scientists with little background knowledge in gene cloning, providing a wealth of information for anyone wishing to gain proficiency in reading and speaking the language of gene cloning.
Author: Dominic W.S. Wong
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 236
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Book Description
Clear and concise, this easy-to-use text offers an introductory course on the language of gene cloning, covering microbial, plant, and animal systems. The essential concepts in biology relevant to the understanding of gene cloning are presented in a well-organized and accessible manner. Consistent with its introductory nature, the book begins by outlining the basic principles of biology and aspects of genetics relevant to the concepts of gene cloning. The next section explores the common techniques and approaches used in gene cloning. The author then discusses various applications in agriculture and food, and in medicine and related areas. The practical uses of gene cloning are extensively illustrated, with specific examples from the literature to demonstrate how gene cloning is conducted utilizing the concepts developed in previous sections. Review questions at the end of each chapter provide self-testing, allowing the reader to assess their understanding of the materials. With more than 90 illustrations, The ABCs of Gene Cloning is an invaluable book for nonscientists as well as scientists with little background knowledge in gene cloning. It provides a wealth of information for anyone with a desire to gain some proficiency in reading and speaking the language of gene cloning. The book covers the essential concepts of gene cloning, paying special attention to explaining jargon in simple, easy-to-understand terms. A unique feature of this book is the inclusion of sample applications of gene cloning in food science, nutrition, and biomedicine, making it a much-needed reference for individuals in these fields who lack formal training in this increasing important area. End-of-chapter exercises and reading assignments are presented to facilitate self study.
Author: Dominic Wong
Publisher: Springer Science & Business Media
ISBN: 0387286799
Category : Science
Languages : en
Pages : 248
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Book Description
Clear and concise, this easy-to-use text offers an introductory course on the language of gene cloning, covering microbial, plant, and animal systems. The essential concepts in biology relevant to the understanding of gene cloning are presented in a well-organized and accessible manner. This updated version of the first edition is an invaluable book for nonscientists as well as scientists with little background knowledge in gene cloning, providing a wealth of information for anyone wishing to gain proficiency in reading and speaking the language of gene cloning.
Author: John N. Abelson
Publisher: Gulf Professional Publishing
ISBN: 9780121821937
Category : Science
Languages : en
Pages : 902
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Book Description
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchersin all fields of life sciences. Prokaryotic ABC Transporters Eukaryotic ABC Transporters Nonmammalian ABC Transport Systems Mammalian P-Glycoproteins Multidrug Resistance Associated Protein Cystic Fibrosis Transmembrane Conductance Regulator Sulfonylurea Receptor Intracellular ABC Transporters
Author: Ahcène Boumendjel
Publisher: John Wiley & Sons
ISBN: 047049512X
Category : Medical
Languages : en
Pages : 480
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Book Description
A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.
Author: I Barry Holland
Publisher: Elsevier
ISBN: 0080481876
Category : Science
Languages : en
Pages : 530
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Book Description
ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. Phylogeny and Evoloution of ABC Transporters Fundamental Aspects of the Mechanism of Action of ABC Transporters Prokaryote ABC Transporters Non-Mammalian Transporters Multidrug Transporters ABC Transporters, Physiological Roles and Human Disease Full color throughout
Author: Drew Provan
Publisher: John Wiley & Sons
ISBN: 1444312685
Category : Medical
Languages : en
Pages : 113
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Book Description
This ABC has established itself as a popular introduction toClinical Haematology, relevant both for postgraduate students andprimary care practitioners. Now in its third edition, the ABC ofClinical Haematology has been thoroughly revised, featuring thelatest treatments for leukemia, antithrombotics and drugs forlymphoma and covering the latest advances in hematology and bonemarrow transplantation. With each chapter written by specialists in their respectivefields, this is an ideal basic text for general practice andhospital staff with patients who have blood related problems, inparticular GPs, hematology nurses, junior doctors, hematologists,and trainees in hematology.
Author: Christopher J. Fielding
Publisher: John Wiley & Sons
ISBN: 9783527625185
Category : Science
Languages : en
Pages : 553
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Book Description
This book meets the long-awaited need for a comprehensive overview of the biological role of HDLs. Edited by one of the pioneers in HDL and cholesterol research, this monograph summarizes current knowledge on HDL turnover, regulation and physiology. Clearly structured, the various sections cover HDL structure, formation, secretion and removal, as well as plasma metabolic factors. The biological activities and clinical aspects are equally discussed, as is the impact of HDL on common diseases and their prevention.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1836
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Book Description
Author: Karobi Moitra
Publisher: Biota Publishing
ISBN: 1615043799
Category : Science
Languages : en
Pages : 84
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Book Description
The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates so far studied. The human ABC transporter superfamily contains 48 genes, subdivided into 7 subfamilies ranging from A to G (based on sequence homology of their nucleotide binding domains). The ABC proteins encoded by these genes are ATP-driven transmembrane pumps, some of which possess the capacity to efflux harmful toxic substances and therefore play a key role in xenobiotic defense. ABC proteins have been evolutionarily conserved from bacteria to humans and multiple gene duplication and deletion events in the ABC genes indicate that the process of gene evolution is still ongoing. Polymorphisms and variations in these genes are linked to variations in expression, function, drug disposition, and drug response. Single nucleotide polymorphisms (SNPs) in these genes could be markers of individual risk for adverse drug reactions or susceptibility to complex diseases. The pharmacogenetics of this unique family of transporters is still under study; however, in the context of human health, it is a well-known fact that variations in these transporters are the underlying cause for several human diseases including cystic fibrosis, Pseudoxanthoma elasticum (PXE), and X-linked adenoleukodystrophy (X-ALD).
